What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022? UW fredhutch SARSCoV2 infection virus covid coronavirus
By Dr. Chinta SidharthanDec 14 2022Reviewed by Danielle Ellis, B.Sc. In a recent study published in JAMA Network Open, researchers evaluated the change in symptoms and risk factors associated with positive severe acute respiratory syndrome coronavirus 2 tests during the coronavirus disease 2019 pandemic and compared it to those associated with positive tests of other respiratory viruses such as rhinovirus among residents of King County, Washington, in the United States.
However, rhinovirus, which causes upper respiratory tract infections in adults and children, has been an exception, with the incidence of rhinovirus infections returning to the original levels after an initial decrease during the early stages of the COVID-19 pandemic. While assessing risk factors, the study considered all the individuals who tested negative for SARS-CoV-2 as the control group, while the individuals who tested positive, including coinfections with rhinovirus, were considered SARS-CoV-2 cases. An additional sensitivity analysis was conducted by excluding coinfection cases.
When symptoms and risk factors were analyzed according to variants of concern, the probability of testing positive for SARS-CoV-2 after close contact with an infected individual and symptoms of anosmia and dysgeusia were lower for the Omicron variant. Individuals infected with the Omicron variant also reported more sore throats than infections with the Delta variant.
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