The impact of environmental exposures in early life on the risk of inflammatory bowel disease (IBD), ulcerative colitis (UC), and Crohn’s disease (CD).
By Tarun Sai LomteMar 13 2024Reviewed by Lily Ramsey, LLM In a recent study published in eClinicalMedicine, researchers examined the impact of environmental exposures in early life on the risk of inflammatory bowel disease , ulcerative colitis , and Crohn’s disease .
Given the rapid loss of natural environments due to biodiversity and climate crises, understanding the role of environmental exposure in health and disease is essential. In cases where participants’ residential municipality changed during this window, a weighted average was assigned for the municipalities. CORINE Land Cover Inventory, with 44 land cover classes and a minimum mapping unit of 25 hectares, was used as the data source for land cover.
Each exposure was categorized into quartiles, with the lowest being the reference. Cox proportional hazard regression was used to investigate associations between exposures and primary and secondary outcomes .
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