Titrzepatide reduces risk of death or worsening heart failure for patients with obesity-related heart failure

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Titrzepatide reduces risk of death or worsening heart failure for patients with obesity-related heart failure
Heart FailureBody Mass IndexClinical Trial
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Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with heart failure, preserved heart pump function and obesity, new research from UVA Health reveals.

University of Virginia Health SystemNov 21 2024 Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with heart failure , preserved heart pump function and obesity, new research from UVA Health reveals.

During that time, 56 placebo recipients died or suffered worsening heart failure, compared with only 36 of those receiving tirzepatide. Further, the tirzepatide recipients were more likely to drop pounds – losing, on average, 11.6% of their body weight. Obesity is a major contributing factor to heart failure, so Kramer and his collaborators in the SUMMIT trial wanted to see if tirzepatide, a weight-loss drug already approved by the federal Food and Drug Administration, could help.

Related StoriesSide effects seen in the tirzepatide group consisted of gastrointestinal issues such as nausea and diarrhea, and these were mostly mild or moderate, the researchers reported Saturday at a meeting of the American Heart Association in Chicago.

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